Gout and rheumatoid have different pathogenesis, clinical manifestations and treatment. 1. Pathogenesis: the onset of gout is related to hyperuricemia. Rheumatoid is caused by immune damage due to autoimmune reaction, which is related to the disorder of the body’s immune system, and the rheumatoid factor is often positive. 2. Clinical manifestations: gout is characterized by the formation of gout stones in the auricle and around the joints. Arthritis caused by gout often starts sharply, with severe pain in the joints, and the attacks are self-limiting, with no symptoms in the intervals. Rheumatoid arthritis usually has a chronic onset, characterized by morning stiffness, mild to severe joint pain, accompanied by joint swelling, and no intermittent period. 3. Treatment: Gout patients usually take uric acid-lowering drugs, such as febuxostat and benzbromarone to reduce uric acid. Rheumatoid commonly used ibuprofen, methotrexate and other drugs to treat. It is necessary to follow the doctor’s instructions to take the relevant drugs. Therefore, gout and rheumatoid rheumatoid are two completely different types of diseases. Patients with rheumatoid or gout manifestations should go to the hospital in a timely manner, timely and clear diagnosis and early treatment.