Sihui San is often used to treat male impotence in male clinics. It is a classic formula composed of Chai Hu, Paeonia lactiflora, Citrus aurantium dulcis and Glycyrrhiza glabra, which is effective in dispersing the liver, regulating the spleen, and relieving depression, and is mainly used for treating the symptoms of distension and pain in the abdomen and ribs, lack of warmth in the hands and feet, or abdominal pain, or diarrhea. If impotence is caused by stagnation of liver qi (liver qi is not flowing smoothly), Si-Wei San can be used to treat it with additional subtractions. If the patient is suffering from emotional disorders, resulting in liver qi stagnation (poor qi and blood transportation of the liver, emotional depression), which will lead to yang qi deficiency for a long time, thus leading to impotence, the treatment should be based on the prescription of dredging the liver and regulating the spleen, penetrating the evils to resolve the depression. At this time, we can use Four Reversals as the basic formula, and then according to the patient’s specific condition, combined with the identification of discretionary addition of yang-strengthening, yin-nourishing, blood-activating and other traditional Chinese medicine treatment. The use of this formula needs to be under the guidance of a doctor, to avoid the adverse consequences of self-medication.