Gout patients taking febuxostat effect is not good may be due to poor dietary habits, not according to the blood uric acid level to adjust the dose of medication or not follow the doctor’s instructions and other factors, according to different reasons to take dietary management, follow the doctor’s instructions to take medication or adjust the dose of medication and other measures. 1. Bad dietary habits: gout patients should pay attention to the diet should be strictly avoided seafood, animal offal, broth and other high-purine diet and limit animal meat, some fish and other purine diet, if the patient is not strictly abstaining from food during the administration of febuxostat, which will lead to unsatisfactory control of uric acid, and in this case, the patient should be advised to strictly abstain from food. 2. Not according to the blood uric acid level to adjust the dose: usually patients taking febuxostat treatment 4 weeks after the hospital should review the blood uric acid level and according to the blood uric acid level gradually increase the dose, if the patient did not adjust the dose according to the blood uric acid level, will lead to uric acid control is not good. This situation leads to poor control of blood uric acid should be recommended to the patient timely review of blood uric acid concentration and timely adjustment of the dose of the drug. 3. Failure to comply with medical advice: patients taking febuxostat tablets during treatment should comply with the doctor’s instructions on time, according to the amount of medication, if the patient does not comply with the doctor’s instructions to take medication may affect the febuxostat blood concentration and thus affect the efficacy of the drug, this should be recommended to the patient to strictly comply with the doctor’s instructions to take medication. Febuxostat should be used under the guidance of a physician, it is recommended that the patient to the rheumatology and immunology department of the regular hospital for detailed consultation, and standardized treatment in accordance with medical advice.