N-terminal brain natriuretic peptide precursors, with normal blood N-terminal brain natriuretic peptide precursor concentrations below 450 pg/ml in adults under 50 years of age and less than 900 pg/ml in people over 50 years of age, have a longer and more stable half-life than BNP, and are more sensitive and specific for the diagnosis of heart failure. The N-terminal brain natriuretic peptide precursor test is important for the diagnosis and prevention of heart failure, as it can be used for the early detection of heart failure patients, the classification of the risk of heart failure, and the monitoring and evaluation of the therapeutic efficacy of heart failure patients. The use of monitoring tools is of great significance and use in the diagnosis and treatment of clinical cardiovascular diseases.