Estradiol tablets are mainly used for the treatment of syndromes caused by estrogen deficiency. Some women may experience menopausal symptoms after menopause or ovariectomy, such as mood changes, emotional instability, hot flashes, excessive sweating, insomnia, excessive dreaming and other clinical symptoms. However, if applied for a long time, adverse reactions may occur, such as breast pain, nausea, or water and sodium retention, swelling and other corresponding clinical symptoms, and occasionally allergies may occur. Therefore, in case of clinical allergy, the drug should be discontinued, and the application of this drug may lead to breast cancer or endometrial cancer, so the drug should be administered only after a thorough evaluation.