Cold hands and feet of a 14-year-old girl may be caused by physiological factors such as sudden feeling of external cold attack and sudden change of climate, or it may be caused by pathological factors such as deficiency of kidney yang, insufficiency of qi and blood, and qi stagnation and blood stasis (blood stagnation due to lack of qi circulation). Kidney-Yang deficiency: Kidney-Yang deficiency cannot warm the limbs, resulting in cold hands and feet. The main treatment is to warm and replenish kidney yang (warming and replenishing kidney yang), which can be done by adding or subtracting Jin Gui Ren Qi Pills. Qi and blood insufficiency: When Qi and blood are insufficient, blood cannot reach the limbs, resulting in cold hands and feet. The main treatment is to replenish qi and nourish blood, which can be done by adding or subtracting Gui Spleen Tang. Qi stagnation and blood stasis: When there is Qi stagnation and blood stasis, the blood cannot reach the limbs well, resulting in cold limbs, hands and feet. The main treatment is to move Qi and activate Blood (to promote the flow of Qi to circulate blood), and can be applied with the addition or subtraction of Hematophagus and Blood Stasis Tang. The adverse effects and contraindications of the above formulae are not yet clear. Physiological conditions: External cold attack and sudden change of climate may lead to cold limbs, hands and feet. Attention should be paid to increase clothing and keep warm in time. When cold hands and feet occur, it is recommended to consult a doctor in time, and after identification by a traditional Chinese medicine practitioner, give Chinese medicines suitable for one’s condition to regulate the body. It is not recommended to take medication at home, so as not to take improper medication and aggravate the condition.