Grumpy and irritable refers to the fact that some people lash out and jump up and down in response to minor stimuli. Grumpiness and irritability is a normal stress response in human beings, and some people react differently to stimuli. Under normal physiological conditions, such people develop this irritable and easy-going temper because they are usually grumpy and irritable. In the pathological state, it is seen in patients with diffuse goiter with hyperthyroidism, which is a pathological state caused by excessive secretion and synthesis of thyroid hormone levels. After the patient has been treated for hyperthyroidism, the state of temper tantrums and irritability decreases when the condition is cured. And there are ordinary people who often lose their temper, and the people next to them did not stop in time, until the intervals between the temper tantrums are more and more, which contributes to this situation, so the behavior of such people is a physiological state, coupled with the outside world does not inhibit the relationship.