Small blisters on the hands need to be identified first, such as sweating herpes, ringworm, eczema, etc., which may lead to small blisters on the hands with itching. It is recommended to do a good job of daily care, but also to give glucocorticoids, antihistamines, antifungal drugs for treatment. 1. Sweat blisters: also known as dyshidrotic eczema, associated with genetic allergic qualities, contact with allergenic substances. In summer, the weather is hot, the skin sweats more, if the sweat is retained locally, it may aggravate herpes perspiration. It can be applied with topical tretinoin and urea ointment, or topical tacrolimus and pimecrolimus ointment to promote the disappearance of blisters and relieve swelling and irritation. 2. Ringworm: ringworm is caused by fungal infections, such as Trichophyton rubrum, Trichophyton rubrum, plaster-like microsporidia, etc., such as blister-type ringworm, which may lead to small blisters on the hands with itching. You can use bifonazole cream, terbinafine cream, miconazole nitrate cream externally, if necessary, with oral itraconazole capsule treatment. 3. Eczema: The cause of eczema is complicated, and it is considered to be related to a variety of internal and external factors, resulting in small blisters on the hands with itching. Treatment of eczema drugs for glucocorticoids, such as topical mometasone furoate cream, hydrocortisone cream and so on. It is recommended to pay attention to daily care, avoid scratching stimulation induced infection, but also to the hospital dermatology department for examination and treatment.