Cerebral infarction does not sleep at night can be treated with eszopiclone, mannitol, antibiotics, etc., drug-induced should be timely adjustment of drugs, and psychological counseling for patients. 1. Caused by increased intracranial pressure: If the patient’s symptom is caused by increased intracranial pressure, he can use sleeping medication, such as eszopiclone, etc. When the patient has cerebral edema, he can use mannitol to reduce the intracranial pressure. 2. caused by infection: some patients with cerebral infarction have secondary infections leading to various discomforts that make it difficult for them to sleep, and they need to use appropriate anti-inflammatory antibiotics, such as penicillin and cephalosporin antibiotics. 3. Drug-induced: some patients use some drugs in the treatment may lead to brain excitability changes, causing patients to have difficulty in falling asleep, this time need to adjust the drugs under the guidance of the doctor. 4. Psychological reasons: some patients can not sleep is due to psychological stress, this time the need for psychological counseling to help patients fall asleep. The use of medication should be under the guidance of a doctor, not unauthorized use of medication.