Myeloma due to individual specific conditions, chemotherapy programs, etc., so the time of effect varies greatly, there is no data to support how long myeloma chemotherapy generally effective. Myeloma patients are generally more sensitive to chemotherapeutic drugs, and combination chemotherapy with multiple drugs is still the most basic treatment for multiple myeloma. The duration of chemotherapy generally needs at least 4-6 courses of treatment, some patients will have more courses of treatment, at the same time, some sensitive patients may get the effect in 1-2 cycles, and the specific time to get the effect varies from person to person. After chemotherapy, most of the remaining tumor cells are in the inactive or quiescent stage, which are often no longer sensitive to chemotherapy and may need to change the treatment plan. Myeloma patients are advised to go to regular hospitals, consult with professional doctors, and cooperate with doctors to complete laboratory tests to avoid blind treatment.