Tongue root oral ulcers can be seen in recurrent aphthous ulcers, or associated with injury, radiation, autoimmune disease, there is no fastest treatment, according to the steps of the general symptomatic treatment using drugs to promote healing, while removing the external stimuli. 1. Symptomatic treatment: tongue root oral ulcers treatment mainly use anti-inflammatory drugs (tretinoin ointment, cidadeine tablets), analgesic drugs (lidocaine gel, benzocaine gel), healing drugs (recombinant human epidermal growth factor gel). 2. Remove irritating factors: remove sharp tooth tips and bad restorations in the mouth, and control the dose of radiation for radiation-induced ulcers. After the emergence of ulcers, the need to maintain a healthy mental state, supplemental nutrition, strengthen physical fitness, relieve tension will help the healing of ulcers, it is recommended to go to the hospital for examination and follow the doctor’s instructions for medication.