Clinical manifestations of cervical disc herniation: 1. Neck stiffness and discomfort or neck and back pain. 2, unilateral limb, finger radioactive pain or numbness, hand numbness and weakness. 3.Tenderness of both lower limbs, weakness of walking and a feeling of stepping on cotton. 4.Dizziness and tinnitus, migraine, eye swelling, panic, nausea, vomiting. Clinical characteristics of cervical disc herniation: 1, the incidence is on the rise. 2. Diversification of symptom expression. 3. The size of herniation is not proportional to the symptoms. 4. Low rate of surgical treatment. 5. The ratio of rupture of the fibrous ring is large, and the simple bulge is small. Minimally invasive treatment methods have been carried out: 1, ozone (O3) injection. 2.Laser decompression. 3.Low temperature plasma radiofrequency ablation. 4.Radiofrequency targeted thermocoagulation. 5.Collagenase lysis. 6.Intradiscal excision and suction. I. Laser intradiscal decompression: Principle: The use of laser high temperature (200 ℃) vaporization of intradiscal nucleus pulposus tissue, the formation of a brief negative pressure zone to reduce the intradiscal pressure, the retraction of the bulging intervertebral disc, to relieve the stimulation or compression of the nerve and spinal cord. Indications: Only for patients with intact annulus fibrosus, elasticity and simple bulge. Methods: The anterior cervical tracheal space is punctured between the paratracheal and vascular sheaths, and the puncture needle is located in the middle of the disc in a frontal and lateral fluoroscopic view, and the laser fiber is introduced to vaporize the nucleus pulposus using laser heat. Advantages and disadvantages: simple operation, little damage, low consumption cost, small scope of indications, high machine cost, not easy to promote the use for cervical disc herniation. Second, radiofrequency target thermal coagulation therapy: principle: the use of radiofrequency needle on the bipolar circuit to generate radiofrequency heat, heating the intervertebral disc nucleus pulposus collagen due to thermal denaturation and volume reduction, retraction and decompression, while the thermo-thermal effect can also block the nerve medium on the nerve root stimulation effect. Indications: rupture of the annulus fibrosus and disc herniation without calcification. Method: Anterior cervical puncture, frontal and lateral fluoroscopy to place the radiofrequency needle at the location of the herniated target (1 or more), test the sensory and motor nerves, and if there is no response, thermocoagulation can be performed from low to high temperature. Advantages: simple operation, basically no consumption cost, relatively low machine cost, wide range of indications. Disadvantages: RF target point selection is very important, in principle, the best effect within the prominence. The range of radiofrequency thermal coagulation is about 5mm, if the prominence is less than 5mm from the nerve, it is not easy to perform thermal coagulation treatment, and the treatment time is long when there are multiple targets. Ozone (O3) injection therapy: Ozone is injected via intervertebral disc puncture in about 10ml, using the strong oxidizing effect of O3 to oxidize part of the nucleus pulposus tissue, which can also reach the herniated area through the fissure of the annulus fibrosus, and play an anti-inflammatory and pain-relieving role at the same time. It is simple to perform, has no consumption cost, and is generally used in combination with other methods. Fourth, low-temperature plasma radiofrequency ablation: principle: radiofrequency electric field in the electrode around the knife head to form a thin layer of plasma (3mm), in which the point ions under the action of strong radiofrequency electric field to obtain enough kinetic energy to break the molecular bonds, so that the target tissue as a unit of molecular disintegration into gas, ablation or cutting in low-temperature conditions. The indications and methods are basically the same as radiofrequency targeted thermal coagulation. Advantages: ablation of the nucleus pulposus tissue at the molecular level under low-temperature conditions is more effective. The ablation conditions are generally non-invasive to the nerve, relatively safer, and no substrate is produced. Disadvantages: Higher cost, suitable for hospitals with considerable strength to carry out. V. Collagenase lysis Principle: The specific lysis effect of collagenase is used to dissolve the collagen fibers in the herniated disc to reduce the size of the herniation and soften it, so as to reduce or relieve the irritation to the nerves and surrounding tissues. Indications: Intradiscal imaging first, if the annulus fibrosus is ruptured and the nucleus pulposus is herniated, lysis is feasible. Method: Target injection method: The needle is inserted in the anterior cervical approach, and the epidural cavity is reached via the intervertebral disc or the stage where the herniation is located. Epidural tube injection method: The needle is inserted between the C6-7 spinous process in the posterior median, and the tip of the needle reaches the epidural, then a microcatheter is inserted, and the catheter is adjusted under fluoroscopy as close as possible to the herniation, and collagenase is injected at 1200u. Advantages and disadvantages: No additional instruments are needed, and the operation is simple. The operation is simple. Intradiscal aspiration: This method is relatively more invasive and has been gradually replaced.