Vaccination does not usually cause elevated creatine kinase. The causes of elevated creatine kinase generally include viral myocarditis or acute myocardial infarction. 1. Viral myocarditis: that is, viral infection induced myocardium with limited or diffuse, acute or chronic inflammatory lesions, which will induce creatine kinase elevation, accompanied by fever and cough and other symptoms. 2. Acute myocardial infarction: myocardial necrosis induced by acute and persistent hypoxia and ischemia of the coronary arteries, the causes of which are generally considered to be related to overexertion, prolonged and excessive smoking and alcohol consumption, which will induce elevation of creatine kinase, accompanied by crushing chest pain. Therefore, it is necessary to go to the regular hospital for further examination and treatment if creatine kinase is elevated after vaccination.