Whether or not you can take cold medicine after drinking alcohol needs to be decided according to the type of cold medicine. It is not advocated to take medicine after drinking alcohol, but certain cold medicines can be taken at the same time after 30-60 minutes of observation after drinking alcohol. There are several categories of cold medicines that you can’t take after drinking alcohol: first, the most common are antibiotics, especially β-lactam antibiotics are particularly significant, representative drugs are cephalosporins and penicillins, such as cefmetazole, cefazolin and other drugs can’t be taken after drinking alcohol. Second, roxithromycin, azithromycin and other macrolides, gentamicin and other aminoglycosides, levofloxacin and other drugs can be taken after drinking alcohol to observe the time to take, more than 6-8 hours after drinking alcohol can try to take a little bit, and observe the clinical symptoms and performance. Thirdly, you can take antiviral cold and flu medicines after drinking, such as ganciclovir, ribavirin, acyclovir and other drugs.