With the liberalization of the two-child policy, the number of people preparing to have a second child is increasing day by day, so what preconception checkups are needed? First note: remember to take folic acid supplementation in the first trimester of pregnancy, 0.4-0.8mg/day, or a multivitamin containing folic acid. Required items: routine blood, routine urine, blood type (ABO and Rh), liver and kidney function, fasting blood sugar, HBsAg, syphilis screening, HIV screening, cervical cytology (if not checked within 1 year). Spare items: TORCH screening (toxoplasma, rubella virus, herpes simplex virus, cytomegalovirus), cervicovaginal discharge test (routine leukorrhea, cervical Chlamydia trachomatis, gonococcus), thyroid function test, 75g OGTT (for high-risk women), lipid screening, pelvic ultrasound, electrocardiogram, chest x-ray.