Weak spermatozoa is a common clinical male disease, patients can take antibiotics (such as azithromycin, etc.), vasodilators (such as pancreatic kallikrein releasing enzyme), anti-hormonal drugs (such as clomiphene, etc.) under the guidance of the doctor. 1. Antibiotics: Antibiotics are mainly used for patients with reduced sperm viability due to germline infections. Patients with mycoplasma or chlamydia infections can be treated with azithromycin, erythromycin, etc. Patients with gonococcal infections can be treated with cephalosporin antibiotics such as ceftriaxone sodium. 2. Vasodilators: vasodilators are mainly used in idiopathic weak spermatogenesis, and commonly used drugs such as pancreatic kinase can improve sperm motility. 3. Anti-hormonal drugs: for endocrine function lowers and idiopathic weak spermatozoa patients, can be used under the guidance of the doctor, such as clomiphene and other drugs for treatment, to promote spermatogenesis. In addition, patients can also take zinc supplements such as zinc gluconate to increase sperm motility. It is recommended that patients strictly follow the doctor’s instructions to use medication, actively cooperate with the doctor’s treatment, in the life of a reasonable arrangement of sexual life, quit smoking and alcohol, can help to promote the recovery of the disease.