There is no clear after-effects report of Xinguan vaccine. There may be slight adverse reactions after the third vaccination, commonly including local reactions and systemic reactions. 1. Local reactions: common inoculation site pain, redness, swelling, itching and other symptoms, generally do not need special treatment, two to three days will be automatically relieved, but pay attention to the inoculation site do not come into contact with water. 2. Systemic reaction: after receiving the new crown vaccine, there is a probability of fever, headache, nausea and other systemic reactions, generally do not need special treatment, will be relieved by themselves. In addition, acute reactions such as anaphylactic shock or syncope may occur after vaccination, requiring prompt rescue treatment. After the third dose of vaccination, there may be local reactions, systemic reactions and other adverse symptoms, it is recommended that timely treatment under the guidance of a doctor according to the symptoms.