A cold with a dry, scratchy throat and a desire to cough may be associated with cold symptoms caused by viral infections, or with other illnesses such as pharyngitis and gastroesophageal reflux disease (GERD). 1. Cold symptoms: The inflammatory mediators induced by viruses lead to a state of afferent nerve hypersensitivity in the upper respiratory tract, which may lead to the symptoms of a cold with a scratchy throat and cough. Secondly, viral infection leads to congestion and edema of the mucous membrane of the throat, which may also lead to symptoms of a dry, itchy throat and a desire to cough. 2. Pharyngitis: Pharyngitis is a diffuse chronic inflammation of the mucous membrane of the pharynx, submucosa and lymphatic tissues, which can have symptoms such as foreign body sensation, itchiness, dryness or slight pain in the pharynx, and if there is discharge of secretion, it can also stimulate the throat with symptoms of wanting to cough. 3. Gastroesophageal Reflux Disease (GERD): Dry and itchy throat and coughing may be caused by gastroesophageal reflux. Due to the reflux of gastric acid, the throat is stimulated, causing symptoms such as itchy throat and cough, which may be accompanied by clinical symptoms such as acid reflux. Dry itchy throat, want to cough may also be caused by other diseases, such as symptoms do not relieve or aggravate, it is recommended to seek medical attention in a timely manner, improve the relevant examination, to clarify the cause of the disease, and follow the doctor’s instructions to carry out the correct treatment.