Physiologic causes is a term used in contrast to pathologic causes, which mainly refers to conditions that occur during normal growth and development. Physiologic causes are generally normal reactions of the body and are not pathological. For example, physiologic jaundice refers to the yellowing of the skin of normal newborns 2-3 days after birth, reaching a peak in 4-5 days and subsiding in about 2 weeks. This is due to the early generation of bilirubin and immature development of liver function, etc. It is a normal physiological phenomenon in the process of neonatal development and usually requires no special treatment. Physiological and pathological jaundice are relative. Pathological jaundice is caused by disease, which requires standardized treatment after clarifying the cause of the disease, otherwise it may affect the growth and development of the child. It is recommended to consult a doctor for assistance in determining whether jaundice is due to physiological or pathological causes, and to follow the doctor’s instructions for standardized treatment after making a clear diagnosis if necessary.