Dense small particles on both sides of the nose may be caused by fat grain, acne, seborrheic dermatitis and other diseases. 1. Fat grain: Fat grain can occur around the eyes, both sides of the bridge of the nose, is caused by certain skin diseases, is a benign lesion, generally do not need special treatment. If there is a need for cosmetic treatment, it can be treated with laser or surgery. 2. Acne: Acne is related to excessive sebum overflow and keratinization of follicular opening, etc. It can occur on the face, chest and back, and shoulders, resulting in non-inflammatory pimples locally. 3. Seborrheic dermatitis: the cause of seborrheic dermatitis has not been fully clarified, and it is considered to be related to heredity, the environment, and the breeding of Malassezia. The lesions tend to occur in areas with high sebum secretion, and can occur on both sides of the nose, resulting in the appearance of many small particles in the local area. It is recommended to pay attention to the cleanliness and hygiene of the face, and if necessary, go to the dermatology department of the hospital to understand the cause before treatment.