Intermittent chills are one of the symptoms of malaria, an infectious disease caused by Plasmodium, characterized by intermittent chills, high fever, sweating and splenomegaly, and anemia. The main purpose of cutting off the transmission route is to eliminate Anopheles mosquitoes and prevent their bites. Remove Anopheles larvae breeding sites and the use of insecticidal drugs. Personal protection can apply repellents or mosquito nets to avoid being bitten by mosquitoes. Control the source of infection, sound epidemic reporting, and eradicate patients with current malaria and those with Plasmodium vivax. Differential diagnosis of intermittent chills: 1. Fever with chills: Fever with chills refers to the symptoms of pathological body temperature increase accompanied by chills due to disease. 2, hyperthermia chills: chills mostly occur before acute febrile illness. Infectious disease causative agent, the role of the body caused by fever, the patient’s whole body chills, goose bumps and shivering, that is, involuntary muscle activity, this is called chills and shivering, referred to as chills. Chills is the precursor of high fever, chills during the period, the body temperature has increased, in the pre-fever is not too high, sometimes the patient only have a general feeling of chills, but no shivering, called chills. 3, the vicious cold: vicious cold, that is, the fear of cold, the fear of cold meaning. The symptom of cold, in the external symptoms of table evidence or Yang deficiency in the evidence can appear. External cold, because the wind and cold in the table, must be accompanied by fever, headache, pulse floating and other surface evidence; Yang deficiency evil cold, is the internal organs of cold, Yang Qi deficiency, must see the body cold, pulse sinking and other cold evidence. In addition, there is also a strong internal heat and external false cold, although the symptoms of malignant cold, cold hands and feet, but the patient is thirsty, breathing gas, constipation, drowning red, the pulse is more slippery solid. 4, trembling: trembling is a regular and repeated involuntary body shaking, can occur in all parts of the body, but the limbs are more. The amplitude can be large or small, the speed can be fast or slow, generally between 1 to 10 times per second.