Patients infected with Helicobacter pylori are advised not to smoke, as there is a risk of aggravating the condition. Helicobacter pylori is a kind of spiral bacteria, this kind of bacteria in the population of the infection rate is relatively high, usually accumulated in the human stomach, it has a close relationship with the human digestive system diseases, Helicobacter pylori infection can lead to chronic gastritis, gastric ulcers, duodenal bulb ulcers, gastric cancer, as well as the gastric mucosa associated lymphoma. Smoking produces certain damage to the gastric mucosa. Nicotine and other components present in tobacco can act on the vagus nervous system, reduce the vasoconstriction of the gastric mucosa, make the blood supply of the gastric mucosa, and destroy the protective factors of the gastric mucosa. Helicobacter pylori itself will be harmful to the gastric mucosa, smoking will aggravate the condition, so Helicobacter pylori infection patients can not smoke. If the patient has Helicobacter pylori, it is recommended to regularly review the C13 breath test, give standardized treatment, quit smoking and drinking, so as not to aggravate the condition.