Low hemoglobin in infants may be a normal physiological phenomenon, or it may be caused by ischemic anemia, immunohaemolytic anemia and other causes. And high platelet in infants may be caused by primary thrombocythemia, acute hemolysis and other reasons. If the infant’s growth and development is relatively rapid may lead to a shortage of hematopoietic raw materials, the infant’s hemoglobin and red blood cells will be lower than the normal value in the routine blood examination, which may be a normal physiological phenomenon. In addition, ischemic anemia, immune hemolytic anemia, aplastic anemia, megaloblastic anemia, blood loss, hemolytic anemia, hereditary spherocytosis and other diseases may also lead to low hemoglobin. Infants presenting with high platelets may be the result of primary disorders such as primary thrombocythemia and true erythrocytosis, as well as dehydration, acute hemolysis, anemia, and acute infections. It is recommended that parents need to take their infants to the doctor promptly if they have low hemoglobin and high platelets, and the doctor will treat the cause of the infant’s condition.