What is suggested by the presence of lingual and insular reddish-orange mucosa above the dentate line of the esophagus?



The presence of ligamentous and insular reddish-orange mucosa above the dentate line of the esophagus suggests Barrett’s esophagus.

The normal esophageal mucosa is a complex squamous epithelium, which appears uniformly pink on gastroscopy but becomes orange when replaced by metaplastic columnar epithelium, mostly located proximal to the dentate line at the junction of the stomach and esophagus, and should be considered Barrett’s esophagus if a circumferential, lingual, or insular lesion of ≥1 cm is present.

Barrett’s esophagus is caused by gastroesophageal reflux disease (GERD), which results in uncomfortable symptoms due to reflux of gastroduodenal contents into the esophagus and invasion of the esophageal mucosa. Typical symptoms are reflux and heartburn. The most accurate way to diagnose Barrett’s esophagus is gastroscopy, which is also capable of determining the severity of the disease and the presence or absence of complications, and Barrett’s esophagus can be seen accordingly under the endoscopy.

Please seek medical advice if you feel unwell.