At 4.5 years of age, six-age teeth are the result of premature growth of the permanent teeth, but it is usually not related to early maturity, and may be due to other reasons, such as apical periapical inflammation of the teeth, which affects the growth of the permanent teeth. The sixth tooth refers to the first permanent molar, which is the sixth tooth counting from the front to the back, and usually starts to grow around the age of 6, so it is called the sixth tooth. There are 4 teeth in total, which are symmetrical, and they are the earliest permanent teeth, and their role is relatively crucial. If they are missing, the other teeth cannot be replaced, so they need to be well protected, and it is important to develop a good habit of brushing in the morning and in the evening. Although the first permanent molar eruption time is usually around 6 years old, but everyone’s physical condition is not the same, the time of tooth replacement is also different, some early, some delayed, half a year in advance as well as delayed half a year are within the normal range. If there is more time in advance, there may be early eruption of teeth, which is generally not related to early maturity. Because early maturation often affects breasts, menstruation, penis, etc., and has no direct relationship with tooth replacement, the big reason is the apical periodontitis, affecting the development of permanent tooth embryo in the alveolar bone, which may appear in the case of early eruption of teeth. In case of severe destruction of the tooth body by apical periodontitis, the diseased tooth needs to be extracted with the help of a doctor.