For inactivated and recombinant New Coronavirus vaccines, if the first two doses are mixed, it is important to monitor yourself for adverse reactions and to complete the correct vaccinations as soon as possible. No special attention is needed for booster shots. If the inactivated and recombinant vaccines are mixed, it may have some effect on the formation of antibodies and the prevention of New Crown. The technical route of the two vaccines is different, so the mixed vaccination will not be able to achieve the purpose of strengthening antibodies. Observe whether there are any adverse reactions, such as fever, nausea and vomiting, localized redness and swelling, etc., and consult a doctor in time. At the same time, after the adverse reactions have been fully treated, consult the staff at the vaccination center and follow the staff’s guidelines to complete the correct vaccination as soon as possible, such as inactivated vaccine as soon as possible to receive the second dose of inactivated vaccine, recombinant protein vaccine to receive the second dose of recombinant protein vaccine, according to the doctor’s instructions. If the inactivated vaccine is given in the first two doses and the recombinant vaccine in the third dose, it is in line with the requirement of sequential vaccination and does not require special attention.