The worsening of some patients’ conditions after radiotherapy is related to factors such as tumor drug resistance, too many side effects and physical weakness. 1. Tumor drug resistance: radiotherapy and chemotherapy are used to treat malignant lesions, and some tumors may be drug resistant or inherently insensitive to chemotherapeutic drugs, so that the use of chemotherapeutic drugs can not achieve the desired effect. 2. Too many side effects: no matter choosing radiotherapy or chemotherapy, it will bring certain damages to the body, and most of the patients will suffer from gastrointestinal discomfort, hair loss, fatigue and other general discomfort after treatment. 3. Weakness: If the patient’s condition is serious, the patient may not be able to tolerate the above treatment and the condition may worsen. Therefore, patients need to pay attention to their own changes during the treatment. If there is any obvious discomfort, you need to seek immediate medical attention.