Gastroscopy identified Helicobacter pylori and atrophic gastritis has been four months, the stomach is always painful these days, there may be lesions such as damage to the gastric mucosa, gastrointestinal disorders, and even gastric cancer occurs. 1. Damage to gastric mucosa: when gastroscopy detects Helicobacter pylori and atrophic gastritis, it will cause damage to the gastric mucosal barrier through the release of toxins and enzymes with toxic effects and mucosal inflammation induced by Helicobacter pylori. 2. Lead to gastrointestinal diseases: Helicobacter pylori and atrophic gastritis can lead to the gastric mucosal tissues of leukocytes, neutrophils and other inflammatory cell aggregation, and further the formation of reactive oxygen radicals, resulting in gastric mucosal necrosis. Then it will lead to a series of gastrointestinal diseases such as gastritis, peptic ulcer, duodenal ulcer, lymphoma of gastric mucosa and other gastrointestinal diseases. 3. Induce gastric cancer: Helicobacter pylori and atrophic gastritis are important initiating factors leading to gastric cancer and its precancerous lesions, and are classified by the World Health Organization as class I carcinogens of gastric cancer. If H. pylori infection exists, H. pylori infection should be eradicated in time, and gastroscopy should be repeated regularly to reduce gastric mucous membrane damage or intestinal metaplasia, so as not to aggravate atrophic gastritis. If stomach pain is frequent or severe, it is recommended to consult a doctor in time, clarify the cause of the disease under the guidance of a physician, and actively treat it to avoid delaying the condition.