Patients with spleen and kidney yang deficiency (deficiency of yang qi in the spleen and kidneys) should not take Liu Wei Di Huang Wan. Most patients with spleen and kidney yang deficiency have a deficiency of yang and yin, and should warm the spleen and kidney yang, and should not take Liu Wei Di Huang Wan, a medicine that nourishes kidney yin. If the symptoms of spleen and kidney yang deficiency are severe, the patient should seek medical advice and use the medication safely under the guidance of a doctor. Spleen and kidney yang deficiency refers to spleen and kidney yang deficiency, belongs to the category of traditional Chinese medicine, for the spleen and kidney yang deficiency, not able to warm up the body, manifested as cold limbs, pale face, waist and knees or lower abdomen cold pain, frequent diarrhea, usually 4 or 5 a.m. diarrhea, commonly discharged incompletely digested food debris, stools are not shaped; or face and limbs swollen, urinary incontinence. Six-flavored Dihuang Pill is mainly composed of the “three tonic” of ripened dihuang, cornelian cherry, yam, and the “three diarrhea” of mudanpi, poria, and zejiao, which has the effect of nourishing yin and tonifying the kidneys. It is often used in treating kidney yin deficiency, lumbar and knee soreness and weakness (the feeling of soreness and weakness in the waist and knees), dizziness, tinnitus, night sweating (abnormal sweating after going to sleep, but the sweating stops after waking up), spermatorrhea, etc. It should be noted that this medicine is not suitable for the treatment of kidney deficiency. It should be noted that, when taking this medicine, avoid spicy food; cold and flu medicines should not be taken during the period of taking the medicine; when symptoms such as loss of appetite, gastric discomfort, loose stools and abdominal pain occur during the period of taking the medicine, go to the hospital; if the symptoms do not improve after 2 weeks of taking the medicine, go to the hospital for consultation.