There are many different types of eye drops and many different effects, and there are differences in the time of use for different types and effects of eye drops: 1. Artificial tear drops: generally can be used for a long time, but it should be noted that artificial tear drops that do not contain preservatives should be used to relieve dry eye symptoms; 2. Antibacterial drug drops: generally fight bacterial infections, so they should not be used for a long time Use. In the acute phase of inflammation can be applied antibacterial drug eye drops, when the inflammation control bacteria subsided, should not continue to use antibacterial drug eye drops. If applied for a long time, it will cause dysbiosis or resistance to antibacterial drugs; 3. IOP-lowering eye drops: In addition, there is a class of eye drops for glaucoma patients to apply IOP-lowering eye drops, which still contain some preservatives, but because of the need to lower IOP, it is also necessary to apply for a long time. But the process of application requires long-term follow-up and regular checkups at the hospital, first to observe the control of IOP and second to observe the irritation that long-term application of eye drops can cause to the eye surface.