Bile reflux gastritis does not usually cause high bilirubin and indirect bilirubin, but the specifics need to be determined by a medical professional. Bile reflux gastritis does not usually cause high bilirubin and indirect bilirubin. Bile reflux gastritis is caused by abnormal duodenal dynamics and inadequate closure of the pylorus, resulting in the reflux of bile from the duodenum into the stomach. High bilirubin and indirect bilirubin may be due to a disease of the liver. Bilirubin is synthesized from hemoglobin, and if hemoglobin breaks down more, it can cause high bilirubin and indirect bilirubin. If you have bile reflux gastritis, you should avoid spicy and stimulating foods in your diet, keep your mood happy, and consult a doctor if you have any other discomforts.