Azoospermia and necrospermia are both more serious, and they are not directly comparable, depending on the development of the disease, its prognosis, and its severity, as follows. 1. Azoospermia: Considering that there is a problem with sperm production or an abnormality in the sperm evacuation pipeline, it means that through three semen tests, no sperm is seen in the sediment after 15 minutes. Some patients can get sperm through testicular puncture sperm retrieval, and then utilize microscopic surgical channel reconstruction’s to achieve the purpose of learning, so it can not be compared with azoospermia. 2. Necrospermia: it is related to the functional lesions occurring in the testicular vas deferens, mainly because the percentage of spermatozoa surviving in the semen is relatively low, while the percentage of inactive spermatozoa is relatively high, thus forming a clinical syndrome, which leads to the inability of men to have children normally. In some patients, sperm quality can be effectively improved by timely removal of the cause, so it cannot be compared with azoospermia. Whether azoospermia or necrospermia, the condition is more serious, and treatment should be carried out actively after diagnosis so as not to delay the condition and lead to reduced fertility.