Medication, surgery, and puncture therapy are viable treatments for patients with epididymal cysts that are painful. Epididymal cysts are cysts that occur on the epididymis. If the patient has no obvious symptoms, usually no special treatment is needed. However, if the patient has pain, it can be treated in the following ways: 1. Medication: For patients with epididymal cysts with cramping sensation and severe pain, oral ibuprofen, acetaminophen and other medications can be taken to relieve the pain. 2. Surgery: Surgical resection is feasible for patients with large epididymal cysts or obvious symptoms and discomfort, but surgical resection carries certain risks and should be used with caution. 3. Puncture and injection: The fluid in the epididymis can be extracted through puncture injection and injected with polyethylene glycol, which can reduce the size of the cyst and relieve the symptoms. It is recommended that patients go to the hospital in time and make treatment plans under the guidance of the doctor. If you need to use drugs, you need to use under the guidance of a doctor.