Thyroid peroxidase antibody is a more sensitive index for detecting autoimmune thyroid disease, its normal value is <60IU/ml, and the current index is about 100IU/ml. If it is physiologically high, no special treatment is needed; however, if it is pathologically high, it should be treated as soon as possible. 1. Physiological high: some healthy people may also have high anti-thyroid peroxidase antibodies, this situation generally does not require special treatment, regular monitoring can be. 2. Pathologically high: for example, subacute thyroiditis, hypothyroidism, chronic lymphocytic thyroiditis, etc. Antithyroid peroxidase antibodies caused by these diseases can be as high as 100IU/ml, and should be treated accordingly. For subacute thyroiditis, prednisone can be given; hypothyroidism should be supplemented with oral thyroxine tablets; for chronic lymphocytic thyroiditis, also known as Hashimoto’s thyroiditis, thyroxine tablets should be used as replacement therapy for those with significant hypothyroidism. If anti-thyroid peroxidase antibody of about 100IU/ml is detected simply, it is recommended to go to the hospital as soon as possible for thyroid function test, thyroid ultrasound and puncture biopsy, etc., to analyze the cause of the disease and then carry out treatment.