Taking isoniazid can cause some damage to liver function, not necessarily cause cirrhosis. Isoniazid is a synthetic anti-infective drug with bactericidal effect, which is the drug of choice for the prevention and treatment of tuberculosis, and it is the drug with the strongest bactericidal effect among all the current anti-tuberculosis drugs. Isoniazid is contraindicated in people who are allergic to isoniazid, in people with hepatic impairment, in people with liver disease, and in people with mental illness. Isoniazid can cause nausea, vomiting, abdominal pain, hemoptysis, allergy, peripheral neuritis, liver function abnormalities and other adverse reactions, persistent liver function abnormalities may lead to cirrhosis of the liver, need to regularly review liver and kidney function. If the above symptoms occur, it is recommended to go to a regular hospital to find a professional doctor for treatment. Drugs should be used under the guidance of a professional physician, and should not be used arbitrarily on their own.