If the acne does not produce pus, mainly because the patient appears to have a deeper inflammatory reaction in the formation of infiltrative spread, and there is no obvious pus, then the main thing is to carry out direct anti-inflammatory treatment. If the inflammation forms a tendency to spread, it also needs to be treated with oral antibiotics, either oral roxithromycin or azithromycin, or, depending on the severity of the inflammation, with oral doxycycline or memantine. Topical anti-inflammatory creams can be applied to the local skin damage, such as fusidic acid cream or mupirocin cream, or topical ichthyolipid ointment.