Abnormal morphology of 70% of red blood cells, accounting for a relatively high percentage, considering a high probability of renal lesions caused by abnormal red blood cell morphology is the formation of aberrant changes in red blood cells as they pass through the basement membrane of the kidney. This situation is often seen in systemic diseases caused by kidney damage, such as hypertensive nephropathy, diabetic nephropathy, nephritis caused by systemic lupus erythematosus, and so on. Targeted tests are needed to confirm the diagnosis, such as renal ultrasound, CT, renal function, etc., and then the exact treatment of different diseases will be carried out. If the patient’s test results in the abnormal form of red blood cells 70%, should pay attention to rest, diet should be light and low-salt, avoid spicy and stimulating food, according to the results of the examination under the guidance of the doctor to standardize the treatment, so as not to miss the condition.