Schizophrenia is a group of psychiatric disorders of unknown etiology, most often starting in young adults, often with a slow onset, with multiple disorders of thought, emotion, behavior, and uncoordinated mental activity. They are usually conscious, have good intelligence, and have a prolonged course with repeated exacerbations or deterioration, but some patients can remain cured or largely cured. It accounts for more than half of the psychiatric inpatients in China. According to a 20-year follow-up of schizophrenia abroad, only 8% of patients recovered completely, and 84% of patients had recurrent episodes, which shows that schizophrenia is a highly recurrent disease. Maintenance treatment for recovering schizophrenic patients is particularly important and is the key to relapse prevention. Patients in recovery generally receive leave from hospital or outpatient treatment, and when their condition allows, family members may grant leave from hospital during long holidays such as double holidays or Chinese New Year. At this time, patients have more opportunities to spend time with their families, and if necessary, they need their families to supervise their daily lives, etc. This requires family members to observe not only the patient’s life and living when they are with him, but also the changes in his condition to see if there are symptoms of This requires the family to observe not only the patient’s daily life but also the changes in his condition when spending time with him, to see if there is any recurrence of symptoms, or what we call the first signs of relapse, in order to control his symptoms as soon as possible. If the patient is not found in time, he may refuse to take the medication, and the patient may not receive timely treatment, making medical care more difficult and even accidents may occur. To determine whether their symptoms are relapsing, the following aspects should be observed: 1. Sleep disorders are often the earliest signs of a relapse of schizophrenia. Patients with no apparent reason have short sleep duration and poor quality, which can manifest as difficulty falling asleep, poor sleep, early awakening, excessive dreaming or nightmares. Due to disease factors, patients with the above conditions are mostly unable to take the initiative to describe them. At this time, family members should closely observe the patient’s sleep, and if sleep problems occur for 2-3 consecutive days, they should promptly contact their doctor and return to the hospital for consultation if necessary. 2, the patient’s mood suddenly becomes often unexplained tantrums, irritable, irritable, nervous, depressed, anxious, etc. 3.Patients often walk back and forth indoors, sometimes go out and do not return, or have sluggish movements, slow reactions, irregular life, laziness, reluctance to get up, daze and froth, and even refuse to take medication, etc. 4. The previous mental symptoms reappear, manifested as the patient’s random thoughts, talking off the board, etc. Such as thinking that others are talking about or persecuting him, feeling that someone is looking at him with bad eyes or following him on the road, feeling that someone is using some kind of instrument to monitor him, etc. 5, attention can not focus, and talk to him as if he did not hear, and always answer “ah, ah” to other people’s questions, or appear various physical discomfort, such as headache, dizziness, weakness of limbs or no appetite. At this time, you should seek medical attention, adjust the treatment plan, and deal with the fluctuations in time to reduce the possibility of disease recurrence.