Prickly heat in infants is mainly caused by the high environmental temperature and the inability of the skin to dissipate heat. The skin should be kept clean and dry, and topical medications should be used to apply it. Prickly heat is caused by high environmental temperature, poor skin heat dissipation, sweat can not be excreted, manifested as small pimples and blisters, itchy and prickly sensation, mostly in the neck, back, shoulders, chest and other parts of the baby prickly heat should be kept clean and dry skin, bathing and changing clothes diligently, the room temperature should be appropriate, in general, in the cooling of the skin, drying and other treatments, prickly heat can be cured by itself, no need for drug treatment. If prickly heat still does not heal spontaneously, some topical medications such as cooling and anti-itching lotion or powder can be used to alleviate the local symptoms, such as glycerite lotion. In addition, if prickly heat causes skin lesions, care should be taken to avoid infection. For bacterial infection, sensitive antibiotics should be used for anti-infection treatment, such as cefixime. Infants should pay attention to the proper care, prickly heat should be timely consultation, under the guidance of the doctor for treatment, pay attention to keep the baby’s skin dry and clean, avoid wrapping too tight. The above medications should be used under medical supervision.