Berytto is the trade name, generic name rivaroxaban, rivaroxaban how long to take need to be based on the underlying disease, such as lifelong medication, 3 to 6 months, and shorter or longer. 1. Rivaroxaban for the treatment of atrial fibrillation requires lifelong medication; for the treatment of lower extremity venous thrombosis, acute pulmonary embolism, usually 3 to 6 months, depending on the circumstances to shorten or extend the treatment time; used for the prevention of thrombosis after hip arthroplasty, usually need to be used until the fracture is fully recovered. 2. Contraindications: patients who are allergic to rivaroxaban or any excipients in the tablets, patients with clinically significant active bleeding, foci or conditions with significant risk of hemorrhage, such as peptic ulcer, pregnant and lactating women. 3. Adverse reactions: taking rivaroxaban may cause bleeding, abdominal pain, dyspepsia, toothache, back pain and other adverse reactions. 4. Precautions: Rivaroxaban should be closely monitored throughout the treatment and early discontinuation of the drug may increase the risk of thromboembolic events. Patients should follow the doctor’s instructions to apply rivaroxaban, do not adjust the dose or stop the drug on their own, so as not to affect the efficacy of the treatment.