Itchy buttock groove may be caused by physiological factors such as inadequate cleaning, or it may be caused by perianal eczema, ringworm and other diseases. 1. Physiological factors: Inadequate local cleaning may cause dirt or bacteria to remain in the local area, leading to itching. 2. Perianal eczema: the etiology is not clear, it may be related to friction, hemorrhoids, genetics and other factors. Patients will have localized erythema, blisters, itching and other symptoms. 3. Ringworm: mainly associated with dermatophyte infection, bad habits, excessive sweating may also induce the disease. Patients will appear local erythema, papules, flaking and other symptoms, accompanied by itching, can be seen in the groin, buttocks and other parts. Itchy buttock groove has more causes, after excluding physiological factors, it is recommended to go to the regular hospital for examination to clarify the cause.