It is best not to take cold and high blood pressure medicines together, even if they need to be taken on the same day there needs to be a time interval. Hypertensive patients need to be careful to take cold medicine containing ephedrine. Clinically, many cold and flu medicines contain pseudoephedrine components, and pseudoephedrine has a vasoconstrictive effect, will raise the patient’s blood pressure and increase the heart rate, resulting in unstable blood pressure control, as well as induced myocardial ischemia and cerebrovascular accidents, so patients with hypertension need to be careful to take cold and flu medicines containing pseudoephedrine. If a hypertensive patient with severe cold symptoms need to take cold medicine, be sure to cold medicine instructions have no hypertensive patients prohibited, as well as check the ingredient list with or without ephedrine, and try to stagger the cold medicine and high blood pressure medication taking time to reduce the negative impact of the interaction of the two drugs.