Yellowing of the skin on the hands may be caused by food factors, anemia, jaundice and other reasons. 1. Food factors: may be eating too much food containing high carotene, the body carotene level appears to rise, resulting in hypercarotenemia. It can be manifested as the symptom of yellowing of the skin of the hands without yellowing of the sclera. 2. Anemia: Under normal circumstances, the color of the skin is not so yellow because there are many capillaries in the skin filled with red blood. However, when anemia occurs in patients, the yellow color of the skin itself will be revealed, resulting in the phenomenon of yellowing of the skin of the hands. 3. Jaundice: It is mainly due to the increased concentration of bilirubin in the serum, which makes the patient’s skin and mucous membranes and even sweat, saliva, urine and so on are yellow stained. In addition, yellowing of the skin on the hands can also be seen in other diseases, it is recommended that patients go to the hospital in a timely manner, in accordance with the doctor’s instructions for treatment, to avoid delaying the condition.