The clinical significance of central venous pressure monitoring can be used in shock patients to guide infusion therapy. Central venous pressure is primarily the blood pressure in the right atrium and the large veins in the thorax. Under normal circumstances, central venous pressure varies generally between 4 and 12 mmHg. If the central venous pressure is found to be significantly or progressively decreased during central venous pressure measurement, it is mainly suggestive of blood volume insufficiency and it is recommended to actively treat it, such as by intravenous infusion, which can replenish blood volume as soon as possible to prevent further decrease in blood volume leading to a drop in blood pressure. When the central venous pressure is measured, the central venous pressure is found to be elevated or progressively elevated, which is considered to be related to the infusion volume being too much and too fast, or it may be caused by the patient’s myocardial contractile insufficiency. It is recommended to slow down the infusion rate or reduce the infusion volume, and give diuretic treatment if necessary. In the case of patients with severe diseases, or the presence of severe cardiac insufficiency, the detection of central venous pressure can more accurately guide clinical treatment.