With the development of social civilization and the gradual improvement of people’s living standards, how to conceive a smart and healthy baby has become the first consideration of every prospective father and mother. Pre-pregnancy checkups are getting more and more attention. Major hospitals have also carried out a series of pre-pregnancy tests. However, because there are many factors that can affect pregnancy and childbearing, the understanding of different doctors is not the same. Different hospitals have introduced different prenatal checkup “packages”, which contain many items and are not uniform, so it is often difficult for the public to choose, and they do not know which hospital is the best place for checkups, and on the other hand, it also aggravates the economic burden of the public. What are the most basic items of prenatal checkup? Generally speaking, the prenatal checkup includes both men and women, and the items are different. For young men and women without a history of genetic disease, adverse pregnancy history, the basic checks are: Men: 1, semen analysis: This test can analyze and reflect the male semen traits, volume and color, PH value, liquefaction time, sperm activity rate, vitality, vitality analysis, sperm density, deformity rate, viability, white blood cells and other dozens of basic semen information, is the most basic, the most important prenatal checkup items. It is the most basic and necessary prenatal examination program. Before the examination, it is required to abstain from sexual intercourse for 3-7 days. 2, semen mycoplasma, chlamydia: mycoplasma, chlamydia is a special microorganism, plain hosted in the mucosal epithelium of the urethra, the vast majority of no obvious symptoms. The disease is non-gonococcal urethritis, is a class II infectious disease, can be transmitted through sex. The male party is very infected, can affect the sperm penetration, reduce the chances of female fertilization, and can be infected with the female party, may become stillbirth, miscarriage and deformed fetus factors. Therefore, the general consensus is that UU or CT should be negative before considering pregnancy. 3, eugenics four (TORCH) eugenics four: including toxoplasmosis, herpes simplex, rubella, megaloblasts four small, it is generally believed that these viruses and micro-organisms can cause fetal malformations, leading to the occurrence of miscarriage, the couple who keep cats, dogs and other small animals at home. 4, Hepatitis B six: Hepatitis B virus can be sexually transmitted, if the man is a hepatitis B patient, you can guide the spouse as soon as possible to inject hepatitis B vaccine, and do a good job of protection, to prevent the man from infecting the woman, and the woman is infected with the fetus, 5, blood type: blood type examination includes the ABO system and the Rh system, the blood type is not compatible with the development of the fetus can be caused by the cessation of fetal development. 6. Physical examination: Physical examination includes basic examination of the whole body, examination of secondary sexual characteristics, and examination of external genitalia. The examination is simple, convenient, but often ignored by doctors, physical examination can provide a lot of important information for clinical. Whether the penis is well developed; whether there is hypospadias and genital malformation, cryptorchidism, whether testicular development is normal, whether there is varicocele and syringomyelia, can be found through physical examination. 7, chromosome karyotype analysis, semen immunological examination and other special tests: not as a routine pre-pregnancy examination program. Only for those who have a family history of genetic diseases; defective child birth history nuclear multiple adverse maternal history and infertility patients can choose to check. Female: 1, gynecological examination, basic examination of the female, including the basic condition of the whole body and the examination of secondary sexual characteristics and external genitalia. 2, Eugenics four tests. 3.Mycoplasma and Chlamydia examination. 4.Hepatitis B six items. 5.Blood type (ABO+Rh). For couples with no adverse maternal history and no history of genetic diseases, the above tests can basically meet the clinical needs.