The time for chronic renal failure stage III to progress to uremia varies from person to person; those with short time can progress to uremia rapidly, and those with long time can maintain their condition for three to five years kidney longer before progressing to uremia. If patients develop serious conditions such as infection or poor control of risk factors, patients will soon progress to uremia. If the patient actively to the nephrology regular diagnosis and treatment, standardized treatment of primary diseases and prevention and treatment of various complications, to avoid or eliminate the deterioration of renal function of the various risk factors, such as blood pressure, lipids, blood sugar, etc., the patient’s progression to uremia will be delayed, can be maintained for three to five years or even more time before progressing to uremia. In addition, the patient’s progression to uremia time, and daily life, diet and sleep factors are also related. Patients should have a regular routine, low-salt, low-fat, high-quality low-protein diet, and avoid exertion, so as to effectively slow down the progression of renal failure. It is recommended that patients with stage 3 kidney failure should consult the hospital in time, under the guidance of the doctor, actively treat the disease and have regular review to avoid the progression of the disease.