The appearance of red spots in the underarm area needs to be combined with clinical symptoms of one’s own sensation and appearance to determine how the factors are formed. If the red spot is flat against the skin and simply tends to be itchy and painful, it is considered to be inter-rub rash, a skin change formed by damage to the epidermis after prolonged sweating and repeated friction in the underarm area. It is recommended to choose to use iodophor solution for disinfection, then wet compress with saline, and then apply glyburide lotion, which will soon bring the symptoms back to normal. If the red dots in the armpit appear raised and itch significantly, it is considered to be eczema and dermatitis resulting in papular changes, and it is recommended to apply fluticasone propionate cream directly for treatment. If the red spots are raised in a linear pattern and do not hurt or itch, it is considered a viral infection that causes filiform warts, and it is recommended to remove them by laser or freezing.