Granuloma hard nodules do not go away generally can be treated by surgery, the specific treatment effect and individual physical condition and the severity of the disease. Early stage of granuloma can be treated with medication, such as levofloxacin eye drops, ibuprofen, etc., whose main effects are anti-infective and antibacterial, anti-inflammatory and analgesic effects. If it is not cured after medication and the hard nodule does not disappear, it can be treated by surgery. During the surgery, it should be noted that the incision should be parallel to the eyelid margin in the case of outer eyelid granuloma, and perpendicular to the eyelid margin in the case of inner eyelid adenitis to prevent damage to the orbicularis oculi muscle. In the case of hard nodules that do not go away, it is recommended to seek medical treatment as soon as possible, and not to take medication without authorization, so as not to delay the condition. Pay attention to rest on weekdays, maintain personal hygiene, quit smoking and drinking, and rationalize your diet.