Patients with chest pain are often seen in thoracic surgery clinics and the identification of the cause is very important. German general practitioners provide the percentage of patients seen with chest pain for the main causes: 11% for stable coronary artery disease, 3.5% for acute coronary syndrome, 46% for chest wall syndrome, 10% for psychological causes, 10% for respiratory infections, and 6% for gastrointestinal causes. The first thing to consider is to exclude acute coronary syndrome, which is commonly known as heart disease, with some clues: acute circulatory insufficiency, syncope and fainting, cold sweats, dyspnea (when quiet), extreme fear in the patient: this condition requires then the need for emergency measures, close monitoring of the condition, inpatient electrocardiogram and other tests for treatment. If the pain reappears at quiet rest and lasts longer than 20 minutes, with cold sweats and pale face, it is very dangerous. Immediate coronary outpatient treatment is required. Panic anxiety disorder – panic confusion attacks; unexplained onset of symptoms (tachycardia, vertigo, dyspnea); nervousness, fear or tension; inability to stop and control anxiety. Depressive disorders – depression, depression or despair; lack of pleasure: loss of interest in the past; somatoform disorders – repeated visits to the clinic despite repeated exclusion of somatic causes due to non-specific disorders. Supported views – localized muscle spasms; tingling; unsupported manifestations on percussion – with dyspnea; respiratory tract infection; cough; known vascular disease. Supported views – duration of illness less than 24 hours, dry cough, diarrhea, fever; presence of cough and sputum; symptoms of chest pain related to breathing.