Irritable bowel for more than 20 years is usually not easy to be cured completely and is more likely to recur, but it can be relieved by active treatment and reduce the possibility of recurrence. Irritable bowel refers to the clinical syndrome including abdominal pain, bloating, abnormal stool characteristics, etc. Irritable bowel is a common functional intestinal disease in clinic, usually without organic lesions. More than 20 years of irritable bowel disease course is longer, so the possibility of cure is more difficult, can follow the doctor’s instructions to take antispasmodic drugs, commonly used drugs such as pivoxyl bromide, antispasmodic drugs can reduce gastrointestinal peristalsis and thus alleviate the irritable bowel. In addition, you can also take drugs to regulate the intestinal flora, such as Bifidobacterium bifidum quadruple live bacterial tablets, Bacillus licheniformis live bacterial capsules, etc., to improve gastrointestinal function by increasing the proportion of beneficial bacteria in the gastrointestinal tract. Irritable bowel is not easy to be cured completely, it is easy to recur, and it is closely related to the individual’s physical and emotional changes, and the diagnosis of the disease needs to exclude other organic lesions, such as suspected irritable bowel should be timely to the hospital for examination, and if the diagnosis needs to be carried out under the guidance of the doctor for scientific and systematic treatment, to avoid delays in the condition.